Active Recombinant Human DPP9 Protein, His-Tagged

• Cat.No.: DPP9-01H
• Product Overview: Spodoptera frugiperda, Sf 21 (baculovirus)-derived human DPP9 protein
  Arg2-Leu892 with an N-terminal Met and 6-His tag

Specification

• Description: This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.
• Source: Sf21 insect cells
• Species: Human
• Tag: His
• Bio-activity: Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC). The specific activity is >750 pmol/min/μg, as measured under the described conditions.
• Molecular Mass: 101 kDa
• N-terminal Sequence Analysis: No result obtained
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -70 °C as supplied.
  3 months, -70 °C under sterile conditions after opening.
• Storage Buffer: Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol.
• Shipping: The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
• Protein length: 2-892 a.a.

Gene Information

• Gene Name: DPP9 dipeptidyl peptidase 9 [ Homo sapiens (human) ]
• Official Symbol: DPP9
• Synonyms: dipeptidyl peptidase 9; Dipeptidyl peptidase IV-related protein 2; dipeptidyl peptidase IV-related protein-2; Dipeptidyl peptidase IX; Dipeptidyl peptidase-like protein 9; dipeptidylpeptidase 9; dipeptidyl-peptidase 9; DKFZp762F117; DP9; DPLP9; DPP IX; DPP9; DPRP2; DPRP-2; EC 3.4.14.5; FLJ16073
• Gene ID: 91039
• mRNA Refseq: NM_001365987.2
• Protein Refseq: NP_001352916.1
• MIM: 608258
• UniProt ID: M0R2A8