Active Recombinant Human DNER Protein, Fc Chimera
| Cat.No. : | DNER-821H |
| Product Overview : | Recombinant Human DNER (Accession # NP_620711), fused with , was produced in Mouse myeloma cell line, NS0-derived. |
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| Source : | Mammalian cells |
| Species : | Human |
| Tag : | Fc |
| Predicted N Terminal : | Arg29 |
| Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
| Bio-activity : | Measured by its ability to inhibit Pleiotrophin-induced neurite outgrowth of E16-E18 rat embryonic cortical neurons.When 4 x 10^4 neurons/well are added to 96-well plate containing serial dilutions of recombinant human DNER Fc chimera and immobilized recombinant human Pleiotrophin/PTN (1 µg/mL), neurite outgrowth is significantly inhibited in a dose dependent manner. The ED50 for this effect is typically 0.4 - 1.6 µg/mL. |
| Molecular Mass : | Recombinant Human DNER, Fc Chimera has a calculated MW of 90.9 kDa (monomer). In SDS-PAGE migrates as 135-160 kDa, reducing conditions. |
| Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Gene Name | DNER delta/notch-like EGF repeat containing [ Homo sapiens ] |
| Official Symbol | DNER |
| Synonyms | DNER; delta/notch-like EGF repeat containing; delta and Notch-like epidermal growth factor-related receptor; bet; UNQ26; H_NH0150O02.1; WUGSC:H_NH0150O02.1; delta-notch-like EGF repeat-containing transmembrane; |
| Gene ID | 92737 |
| mRNA Refseq | NM_139072 |
| Protein Refseq | NP_620711 |
| MIM | 607299 |
| UniProt ID | Q8NFT8 |
| Chromosome Location | 2q36.3 |
Not For Human Consumption!
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