DNER

  • Official Full Name

    delta/notch-like EGF repeat containing
  • Overview

    Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.
  • Synonyms

    DNER;delta/notch-like EGF repeat containing;delta and Notch-like epidermal growth factor-related receptor;bet;UNQ26;Brain EGF repeat-containing transmembrane protein;Bret;Delta/notch-like EGF-related receptor;DNER_HUMAN;Transmembrane protein Bet;H_NH0150O02.1;OTTHUMP00000204223;WUGSC:H_NH0150O02.1;delta-notch-like EGF repeat-containing transmembrane

Recombinant Proteins

  • Mouse
  • Human
  • Zebrafish
  • Mammalian cells
  • HEK293
  • Wheat Germ
  • Mammalian Cell
  • E.coli
  • Non
  • Fc
  • Flag
  • GST
  • His
  • His&Fc
  • His&T7
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
Dner-410M Active Recombinant Mouse Delta/Notch-Like EGF-Related Receptor Mammalian cells Mouse Non 26-637 a.a.
DNER-821H Active Recombinant Human DNER Protein, Fc Chimera Mammalian cells Human Fc
Dner-838M Active Recombinant Mouse Dner Protein, Fc Chimera Mammalian cells Mouse Fc
DNER-2080H Recombinant Human Delta/notch-like EGF Repeat Containing, Fc Chimera HEK293 Human Fc 1-637 a.a.
DNER-26158TH Recombinant Human DNER, FLAG-tagged HEK293 Human Flag 640 amino acids
DNER-2784H Recombinant Human DNER Protein, GST-tagged Wheat Germ Human GST
DNER-28368TH Recombinant Human DNER, Fc-tagged HEK293 Human Fc 637 amino acids
DNER-4733M Recombinant Mouse DNER Protein Mammalian Cell Mouse His
DNER-835H Recombinant Human DNER Protein, His tagged HEK293 Human His 29-637 aa
DNER-8380Z Recombinant Zebrafish DNER Mammalian Cell Zebrafish His
DNER-1245H Recombinant Human DNER protein, hFc&His-tagged HEK293 Human His&Fc Arg29-His637
DNER-1812H Recombinant Human DNER protein, His & T7-tagged E.coli Human His&T7 Glu339~Asn583
DNER-2272H Recombinant Human DNER Protein (Glu339-Asn583), N-His tagged E.coli Human His Glu339-Asn583
Dner-25M Recombinant Mouse Dner Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
Dner-25M-B Recombinant Mouse Dner Protein Pre-coupled Magnetic Beads HEK293 Mouse
DNER-49H Recombinant Human DNER Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
DNER-49H-B Recombinant Human DNER Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    DNER involved in several pathways and played different roles in them. We selected most pathways DNER participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus,Notch signaling pathway,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNER were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Notch signaling pathway DLA,HDAC2,JAG2B,NCOR2,MFAP5,CTBP2A,RBPJ,DTX4,DTX3,LNX1
    Signaling by NOTCH MDK,TLE3,DLK1,DTX2,RAB6A,TLE4,HEYL,MDKA,TLE2,MDKB
    Signaling by NOTCH1 DLK1,TLE3,HEYL,DTX2
    Activated NOTCH1 Transmits Signal to the Nucleus DTX2,MIB1,JAG1,DLK1,CNTN1,ADAM10,JAG2
    Signal Transduction WIF1,IFT52,ANXA1B,SHB,FST,FGD4A,CBY1,LIN7B,OPN4.1,FGD2

    Protein Function

    DNER has several biochemical functions, for example, Notch binding,calcium ion binding,clathrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNER itself. We selected most functions DNER had, and list some proteins which have the same functions with DNER. You can find most of the proteins on our site.

    Function Related Protein
    transmembrane signaling receptor activity GPR124,FZD3A,PTH1RA,OR12D2,OR12D3,GP6,SLAMF1,ADCYAP1R1A,CD27,KLRC2
    protein binding NEU2,IGSF1,MEIOB,SHANK3,ANLN,MXD4,EIF2S1,ISOC1,ZNF473,MYC
    clathrin binding SYTL1,TOM1,SNAP91,AP2B1,SYT8,AFTPH,LDLRAP1,PICALM,SYT15,SYTL2
    calcium ion binding PLCB2,TMEM8C,PCDHGA1,MYL12B,PCDH1G3,FSTL1A,LRP2A,RYR2,PCDH1G2,ANXA5B
    Notch binding C8orf4,NOTCH1,HIF1AN,CHAC1,DLL3,NOV,GALNT11,JAG1A,EGFL7,AAK1

    Interacting Protein

    DNER has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNER here. Most of them are supplied by our site. Hope this information will be useful for your research of DNER.

    ZNF24

    DNER Related Signal Pathway

    Resources

    Research Area

    Notch Family

    References

    • Honnorat, J; et al. Therapeutic approaches in antibody-associated central nervous system pathologies. REVUE NEUROLOGIQUE 170:587-594(2014).
    • Greene, M; Lai, YJ; et al. DNER Antibodies in Patients with Anti-Tr, Paraneoplastic Cerebellar Degeneration, and Hodgkin's Lymphoma. ANNALS OF NEUROLOGY 76:S78-S78(2014).

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