Active Recombinant Human CLEC5A Protein, Tyr26-Lys188, N-9×His tagged

• Cat.No.: CLEC5A-12H
• Product Overview: Recombinant Human MDL-1/CLEC5A Protein (Tyr26-Lys188) with an N-terminal 9-His tag was expressed in Mouse myeloma cell line.

Specification

• Description: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.
• Source: Mouse myeloma cell line
• Species: Human
• Tag: N-9×His
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human Galectin-9 is coated at 0.5 μg/mL (100 μL/well), the concentration of Recombinant Human MDL-1/CLEC5A that produces 50 % optimal binding response is typically 3-18 ng/mL.
• Molecular Mass: Predicted Molecular Mass: 20 kDa
  SDS-PAGE: 34-45 kDa, reducing conditions
• Protein length: Tyr26-Lys188
• N-terminal Sequence Analysis: His
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 95 %, by SDS-PAGE with silver staining
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: CLEC5A C-type lectin domain family 5, member A [ Homo sapiens (human) ]
• Official Symbol: CLEC5A
• Synonyms: CLEC5A; C-type lectin domain family 5, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 5 , CLECSF5; C-type lectin domain family 5 member A; MDL 1; C-type lectin superfamily member 5; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; MDL1; MDL-1; CLECSF5; MGC138304
• Gene ID: 23601
• mRNA Refseq: NM_013252
• Protein Refseq: NP_037384
• MIM: 604987
• UniProt ID: Q9NY25