CLEC5A
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Official Full Name
C-type lectin domain family 5, member A -
Overview
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008] -
Synonyms
CLEC5A;C-type lectin domain family 5, member A;MDL1;MDL-1;CLECSF5;C-type lectin domain family 5 member A;C-type lectin superfamily member 5;myeloid DAP12-associating lectin 1;myeloid DAP12-associating lectin-1;C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5
Recombinant Proteins
- Human
- Mouse
- Rat
- Cynomolgus
- Rhesus macaque
- E.coli
- Mammalian cells
- NS0
- HEK293
- Wheat Germ
- Human Cell
- Mammalian Cell
- Insect Cell
- In Vitro Cell Free System
- His
- N-9×His
- Fc
- GST
- Non
- mFc
- His&Fc&Avi
Involved Pathway
CLEC5A involved in several pathways and played different roles in them. We selected most pathways CLEC5A participated on our site, such as DAP12 interactions,Immune System,Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | ALCAMB,ASB13,TRIM38,HUWE1,CNPY3,ASB11,NA,BTR29,TXN,CLEC4A |
| DAP12 interactions | DUSP4,CD300LB,GRAP2B,DUSP1,MOV10,SPTB,GRAP2A,NEFLB,TREM1,CNKSR1 |
| Innate Immune System | POLR3F,PELI3,BTR18,TRIM56,C1rb,FAM49BA,SUGT1,CFHL2,MYO9B,MASP2 |
Protein Function
CLEC5A has several biochemical functions, for example, carbohydrate binding,virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC5A itself. We selected most functions CLEC5A had, and list some proteins which have the same functions with CLEC5A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | OS9,REG3G,REG1B,CHI3L2,ZG16B,ATRN,Mgl2,GALNT6,CALR3,CLEC4D |
| virus receptor activity | AXL,SLC52A2,DPP4,GPR172B,ITGB5,NPC1,EFNB3,HSPA1B,EFNB2,ITGA2 |
Interacting Protein
CLEC5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC5A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC5A.
Resources
Research Area
ITIM/ITAM Immunoreceptors and Related MoleculesC-type Lectin Receptors
Dendritic Cell Activation
Dendritic Cell ITIM/ITAM Immunoreceptors
C-type Lectin Family
Related Services
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References
