Active Recombinant Human Chemokine (C-C motif) Ligand 24, MIgG2a Fc-tagged

• Cat.No.: CCL24-102H
• Product Overview: The extracellular domain of human CCL24 (AAH69391.1) (Val27-Cys119) is fused to the N-terminus of the Fc portion of mouse IgG2a was expressed in CHO celL

Specification

• Description: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line
• Source: CHO cells
• Species: Human
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to chemoattract Y3 rat myeloid cells transfected with human CCR3.
• Molecular Mass: 37 KDa (monomer)
• AA Sequence: Val27-Cys119
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.
• Protein length: 27-119 a.a.

Gene Information

• Gene Name: CCL24 chemokine (C-C motif) ligand 24 [ Homo sapiens ]
• Official Symbol: CCL24
• Synonyms: CCL24; chemokine (C-C motif) ligand 24; SCYA24, small inducible cytokine subfamily A (Cys Cys), member 24; C-C motif chemokine 24; CK beta 6; Ckb 6; eotaxin 2; MPIF 2; MPIF2; myeloid progenitor inhibitory factor 2; CK-beta-6; eotaxin-2; small-inducible cytokine A24; eosinophil chemotactic protein 2; small inducible cytokine subfamily A (Cys-Cys), member 24; Ckb-6; MPIF-2; SCYA24
• Gene ID: 6369
• mRNA Refseq: NM_002991
• Protein Refseq: NP_002982
• MIM: 602495
• UniProt ID: O00175
• Chromosome Location: 7q11.23
• Pathway: Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: chemokine activity