Recombinant Human ACVR1B Protein, Fc-tagged
Cat.No. : | ACVR1B-082H |
Product Overview : | Recombinant human ACVR1B protein with Fc tag was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | Fc |
Protein Length : | 505 |
Description : | This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants. |
Form : | Lyophilized |
Molecular Mass : | 38 kDa |
AA Sequence : | MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI |
Purity : | > 98% |
Applications : | WB; ELISA; FACS; FC |
Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : | At -20 centigrade. |
Concentration : | 1 mg/mL |
Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
Gene Name | ACVR1B activin A receptor, type IB [ Homo sapiens (human) ] |
Official Symbol | ACVR1B |
Synonyms | ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB; |
Gene ID | 91 |
mRNA Refseq | NM_004302 |
Protein Refseq | NP_004293 |
MIM | 601300 |
UniProt ID | P36896 |
◆ Recombinant Proteins | ||
ACVR1B-529H | Active Recombinant Human ACVR1B protein, hFc-tagged | +Inquiry |
Acvr1b-5598M | Recombinant Mouse Acvr1b Protein (Leu32-Glu126), C-Fc tagged | +Inquiry |
ACVR1B-1916H | Active Recombinant Human Activin A Receptor, Type IB | +Inquiry |
ACVR1B-1289H | Recombinant Human ACVR1B Protein (N150-I505), His tagged | +Inquiry |
ACVR1B-2596H | Recombinant Human Activin A Receptor, Type IB | +Inquiry |
◆ Cell & Tissue Lysates | ||
ACVR1B-1356CCL | Recombinant Cynomolgus ACVR1B cell lysate | +Inquiry |
ACVR1B-2130HCL | Recombinant Human ACVR1B cell lysate | +Inquiry |
ACVR1B-1206RCL | Recombinant Rat ACVR1B cell lysate | +Inquiry |
Not For Human Consumption!
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