Active Native Ricinus Communis Agglutinin II Protein

• Cat.No.: Lectin-1834R
• Product Overview: This product is the Unconjugated Ricinus Communis Agglutinin II (RCA II, RCA60, ricin) and has sugar specificity against Galactose, N-Acetylgalactosamine, and Lactose.

Specification

• Species: Ricinus Communis
• Source: Ricinus Communis
• Tag: Non
• Description: Ricinus communis agglutinin II is an extremely toxic glycoprotein consisting of two disulfide-linked chains of about 28 kDa and 32 kDa, termed A and B chain, respectively. The B chain can bind to cell surfaces via galactose or N-acetylgalactosamine residues of membrane glycoconjugates and facilitates the transport of the lectin into the cell. The A chain has an enzyme activity which can catalytically block protein synthesis and is so toxic that only a single molecule of A chain is required to kill a cell. Alone, the A chain is incapable of entering the cell and is thus not toxic.
• Form: 10 mM phosphate, 0.15 M NaCl, pH 7.8, 0.08% sodium azide
• Bio-activity: Inhibiting/Eluting Sugar: 200 mM galactose or lactose
• Molecular Mass: 60 kDa
• Applications: Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Glycobiology
• Usage: THIS IS A TOXIC LECTIN! EXERCISE CAUTION IN ITS USE! NEVER PIPET SOLUTIONS OF THIS LECTIN BY MOUTH. DO NOT LYOPHILIZE!
• Storage: Store at 4 centigrade
• Concentration: 5.0 mg/ml

Gene Information

• Synonyms: Lectin; RCA II, RCA 60, ricin
• UniProt ID: P02879