Active Native Clostridium perfringens Neuraminidase Agarose, Type VI-A

• Cat.No.: Neuraminidase-013C
• Product Overview: Type VI-A, ammonium sulfate suspension

Specification

• Species: Clostridium perfringens (C. welchii)
• Description: Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.
• Form: ammonium sulfate suspension
• Enzyme Commission number: 3.2.1.18 (BRENDA, IUBMB)
• MDL number: MFCD00131711
• UNSPSC Code: 12352204
• NACRES: NA.54
• Matrix: Beaded agarose
• Bio-activity: 20-60 units/g agarose
• Unit Definition: One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37 centigrade using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate.
• Applications: Agarose-linked neuraminidase from Clostridium perfringens can be used for the detection of total and desialylated sex hormone-binding globulin in human serum samples.
  Neuraminidase from Clostridium perfringens has been used in a study to assess a genetic polymorphism of human serum glycoprotein (inter-α-trypsin-inhibitor). It has also been used in a study to investigate the inhibition of neuraminidase by chemically sulphated glycopeptides.
• Storage: 2-8 centigrade
• Storage Buffer: Suspension in 2.0 M (NH4)2SO4 solution, pH 7.0.

Gene Information

• Official Symbol: Neuraminidase
• Synonyms: Acylneuraminyl hydrolase; Receptor-destroying enzyme; Sialidase