Active GMP Recombinant Human CD40L Protein

• Cat.No.: CD40LG-01HG
• Product Overview: Recombinant human CD40LG protein, was expressed in CHO-K1 cell-derived in an animal component free process under cGMP guidelines.

Specification

• Species: Human
• Source: CHO
• Description: The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
• Form: Lyophilized powder
• Endotoxin: <20 EU/mg
• Bio-activity: >1.0 x 10^5 IU/mg
• Purity: >95.0% by high performance liquid chromatography (SEC-HPLC) and SDS-PAGE.
• Storage Buffer: 10mM Phosphate-Buffered Saline (pH 7.2)
• Storage: Stable storage at 4℃ for 7-10 days; for long-term storage, please store at -20℃ after dispensing.
• Sterility: Sterility
• Instructions: It is recommended that lyophilized GMP rhCD40LG be dissolved in water for injection or sterilized ultrapure water at a concentration of not less than 100 μg/ml, pending further dilution to working concentration.

Gene Information

• Gene Name: CD40LG CD40 ligand [ Homo sapiens (human) ]
• Official Symbol: CD40LG
• Synonyms: IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
• Gene ID: 959
• mRNA Refseq: NM_000074.3
• Protein Refseq: NP_000065.1
• UniProt ID: P29965
• MIM: 300386