Synthetic Human Di-ubiquitin (K6-linked) Protein

• Cat.No.: UBA52-03H
• Product Overview: Synthetic Human Di-ubiquitin (K6-linked) Protein

Specification

• Description: Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome.
• Source: Synthetic/chemical ligation
• Species: Human
• Molecular Mass: ~17.1 kDa
• AA Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
• Purity: >98% by InstantBlue SDS-PAGE
• Stability: 12 months at -70 centigrade; aliquot as required
• Storage: At -70 centigrade.
• Concentration: 0.5 mg/mL
• Storage Buffer: 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol

Gene Information

• Gene Name: UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 [ Homo sapiens (human) ]
• Official Symbol: UBA52
• Synonyms: UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1; L40; CEP52; RPL40; HUBCEP52; ubiquitin-60S ribosomal protein L40; ubiquitin carboxyl extension protein 52; ubiquitin-52 amino acid fusion protein; ubiquitin-CEP52
• Gene ID: 7311
• mRNA Refseq: NM_003333
• Protein Refseq: NP_003324
• MIM: 191321
• UniProt ID: P62987