UBE2D3
-
Official Full Name
ubiquitin-conjugating enzyme E2D 3 -
Overview
Protein ubiquitination requires the concerted action of the E1, E2 and E3 ubiquitin-conjugating enzymes. Ubiquitin is first activated through an ATP-dependent formation of a thiol ester with an E1 enzyme. The activated ubiquitin is then transferred to a t -
Synonyms
UBE2D3;ubiquitin-conjugating enzyme E2D 3;ubiquitin conjugating enzyme E2D 3 (homologous to yeast UBC4/5) , ubiquitin conjugating enzyme E2D 3 (UBC4/5 homolog, yeast);ubiquitin-conjugating enzyme E2 D3;UbcH5C;E2(17)KB 3;ubiquitin-protein ligase D3
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- Chicken
- Rhesus macaque
- Rat
- Zebrafish
- Human/Mouse/Rat
- E.coli
- Mammalian Cell
- HEK293
- Insect Cell
- E. coli
- HEK293T
- GST
- His
- Non
- His&Strep
- His&SUMO
- His&Fc&Avi
- Myc&DDK
Involved Pathway
UBE2D3 involved in several pathways and played different roles in them. We selected most pathways UBE2D3 participated on our site, such as Ubiquitin mediated proteolysis,Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2D3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | TRAF6,FBXW11,UBE2L3B,FBXO2,PPIL2,ANAPC13,SIAH1A,UBE2IA,UBE2I,FBXO4 |
| Protein processing in endoplasmic reticulum | SEL1L,SEC24B,SEC23B,MBTPS1,SEC61G,HSPA5,ERN1,UBE2E1,SSR2,ERO1LB |
Protein Function
UBE2D3 has several biochemical functions, for example, ATP binding,protein binding,ubiquitin conjugating enzyme activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2D3 itself. We selected most functions UBE2D3 had, and list some proteins which have the same functions with UBE2D3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | MYO1H,OBSCN,DDX3,PAPSS1,SLC27A2,ACSM2,ATAD3A,TOR2A,TEC,CHD1 |
| ubiquitin conjugating enzyme activity | UBE2Q2,UBE2G2,UBE2J1,UBE2E2,UBE2D2A,UBE2O,UBE2L3,UBE2Z,UBE2C,UBE2N |
| ubiquitin-protein transferase activity | RNF31,TRIM71,LMO7,UBE3A,RNF217,AMFR,PRKCQ,MKRN1,ANKIB1,BIRC5B |
| protein binding | GNB3,ATP5A1,C1orf109,PCBP1,SLC39A7,C21orf7,APOBEC3C,ACTN2,NFKBIE,FZD3 |
Interacting Protein
UBE2D3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2D3 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2D3.
RNF5;OTUB1;RNF111;TRIM39
Resources
Related Services
Related Products
References
