TTYH1
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Official Full Name
tweety homolog 1 (Drosophila) -
Overview
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
TTYH1;tweety homolog 1 (Drosophila);tweety (Drosophila) homolog 1;protein tweety homolog 1;hTTYs;TTYH 1;Tweety 1;Tweety homolog 1;Tweety1;hTTY1;OTTHUMP00000068178;OTTHUMP00000068179;OTTHUMP00000068180
Recombinant Proteins
- Cynomolgus
- Mouse
- Human
- Mus musculus
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Rat
- Bovine
- Macaca fascicularis
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
TTYH1 involved in several pathways and played different roles in them. We selected most pathways TTYH1 participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with TTYH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SRI,SLC29A3,SLC28A2,ATP7B,SLC13A2,SLC13A3,CLCA1,ABCA7,ABCD3B,SLC6A20 |
| Stimuli-sensing channels | MCOLN2,ANO5B,ANO10A,CLCN6,TRPM6,TRPC4APA,ANO9,CLCN1A,ANO5,TRDN |
| Ion channel transport | ATP13A,CLCA1,FXYD6,SLC9A10,TRPC4B,ANO1,BEST3,CLCN2,CCC2,ATP1A1A.3 |
Protein Function
TTYH1 has several biochemical functions, for example, calcium ion binding,iron ion transmembrane transporter activity,volume-sensitive chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TTYH1 itself. We selected most functions TTYH1 had, and list some proteins which have the same functions with TTYH1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron ion transmembrane transporter activity | SLC40A1 |
| calcium ion binding | PCDH1G29,FBLN7,UMODL1,PKD1L2,PCDH2G1,RCV1,MMP3,EFCAB4B,RHOT2,SCGN |
Interacting Protein
TTYH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TTYH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TTYH1.
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