IGFBP5
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Official Full Name
insulin-like growth factor binding protein 5 -
Overview
Insulin-like growth factor-binding protein 5 is a protein that in humans is encoded by the IGFBP5 gene. -
Synonyms
IGFBP5;insulin-like growth factor binding protein 5;IBP5;insulin-like growth factor-binding protein 5;IBP-5;IGFBP-5;IGF-binding protein 5;Insulin-like growth factor-binding protein 5
Recombinant Proteins
- Rat
- Human
- Mouse
- Cynomolgus
- Canine
- E.coli
- yeast
- Mammalian Cells
- HEK293
- Human Cells
- Insect Cells
- Non
- His
- Fc
- Avi&Fc&His
- His&Myc
Involved Pathway
IGFBP5 involved in several pathways and played different roles in them. We selected most pathways IGFBP5 participated on our site, such as Metabolism of proteins,Myometrial Relaxation and Contraction Pathways,Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | IGFBP6A,IGFBP2,IGFBP5A,IGFBP2A,IGFBP6B,KLK13,PAPPA,IGFBP1B,PAPPA2,IGFBP4 |
| Senescence and Autophagy | MAP1LC3C,IGFBP7,SLC39A1,AMBRA1,COL10A1,SLC39A3,GABARAPL2,CREG1,FKBP8,ING1 |
| Myometrial Relaxation and Contraction Pathways | IGFBP6,GUCA2A,PKIB,RGS17,CORIN,RAMP2,RGS19,RGS11,ADM,RGS16 |
| Metabolism of proteins | BCHE,ST8SIA3,TRAPPC4,CALCA,ADAMTSL3,DPH1,ARSH,MLEC,EEF1A2,ST6GAL2B |
Protein Function
IGFBP5 has several biochemical functions, for example, fibronectin binding,insulin-like growth factor I binding,insulin-like growth factor II binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP5 itself. We selected most functions IGFBP5 had, and list some proteins which have the same functions with IGFBP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| insulin-like growth factor I binding | IGFBP2A,IGFBP5A,IGFBP6B,IGFBP2B,IGF1R,IGFBP6A,IGFBP1B,IGFBP2,IGFBP3,IGFBP4 |
| protein binding | PSMC4,BTRC,PMAIP1,FAS,DNPEP,FAM189B,DIS3,C2orf29,JAM3,CUBN |
| insulin-like growth factor II binding | IGFBP2B,IGFBP3,IGFBP6,IGFBP4,IGFBP1A,IGFBP5B,IGFBP6A,IGFBP2A,IGFBP6B,IGFBP5A |
| fibronectin binding | VEGFA,MMP13,FBLN1,CTSL1,IGFBP3,MFAP2,CTSS,LACRT,ITGB1A,IGFBP5A |
Interacting Protein
IGFBP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP5.
BAG6;FHL1;PNO1
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References
- Ha, S; Iqbal, NJ; et al. Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer. ONCOGENE 32:3992-4000(2013).
- Pavlicek, A; Lira, ME; et al. Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871). MOLECULAR CANCER THERAPEUTICS 12:2929-2939(2013).
