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HECTD2

Official Full Name

HECT domain containing E3 ubiquitin protein ligase 2
Synonyms

HECTD2; HECT domain containing E3 ubiquitin protein ligase 2; HECT domain containing 2; probable E3 ubiquitin-protein ligase HECTD2; FLJ37306; HECT domain-containing protein 2; FLJ16050;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse

Source

E. coli
HEK293
HEK293T
In Vitro Cell Free System
Wheat Germ

Tag

C
Flag
GST
His
Myc
DDK
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	HECTD2-4677H	Recombinant Human HECTD2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	HECTD2-5591HCL	Recombinant Human HECTD2 293 Cell Lysate	HEK293	Non		Inquiry
Human	HECTD2-4H	Recombinant Human HECT domain E3 ubiquitin protein ligase 2 Protein, Flag tagged	HEK293T	C-Flag		Inquiry
Human	HECTD2-20H	Recombinant Human HECTD2 protein, His-tagged	E. coli	His	428-776 a.a.	Inquiry
Human	HECTD2-2241H	Recombinant Human HECTD2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Human	HECTD2-21H	Recombinant Human HECTD2 protein, His-tagged	E. coli	His	21-170 a.a.	Inquiry
Human	HECTD2-3459HF	Recombinant Full Length Human HECTD2 Protein, GST-tagged	In Vitro Cell Free System	GST	207 amino acids	Inquiry
Mouse	Hectd2-3378M	Recombinant Mouse Hectd2 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

HECTD2 involved in several pathways and played different roles in them. We selected most pathways HECTD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HECTD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

HECTD2 has several biochemical functions, for example, ligase activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HECTD2 itself. We selected most functions HECTD2 had, and list some proteins which have the same functions with HECTD2. You can find most of the proteins on our site.

Function	Related Protein
ligase activity	DTX1;UBR4;PPIL2;MID2;LTN1;PIAS3;RNF126;TRIM22;RNF138
ubiquitin protein ligase activity	MGRN1;TRIM63;CDC42;MED21;UBE2V1;RNF152;RNF122;XIAP;UBE2J2

HECTD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HECTD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HECTD2.

ACKR3

Research Area

Vina-Vilaseca, A; Sorkin, A; et al. Lysine 63-linked Polyubiquitination of the Dopamine Transporter Requires WW3 and WW4 Domains of Nedd4-2 and UBE2D Ubiquitin-conjugating Enzymes. JOURNAL OF BIOLOGICAL CHEMISTRY 285:7645-7656(2010).