FCGR3B
-
Official Full Name
Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -
Overview
FCGR3B (Fc fragment of IgG, low affinity IIIb, receptor), also known as CD16b (Cluster of Differentiation 16b), is a human gene. -
Synonyms
FCGR3B;Fc fragment of IgG, low affinity IIIb, receptor;CD16b;Cluster of Differentiation 16b;FCGR3B;CD16;CD16b;FCG3;FCGR3;FCR-10;FCRIII;FCRIIIb
Recombinant Proteins
- Human
- HEK293
- E.coli
- Mammalian Cells
- CHO
- Human Cells
- Insect Cells
- His
- Non
- Avi&His
- Fc&His
- His&T7
- Flag
- Avi&Fc&His
- GST&His&Myc
Involved Pathway
FCGR3B involved in several pathways and played different roles in them. We selected most pathways FCGR3B participated on our site, such as Phagosome,Osteoclast differentiation,Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Osteoclast differentiation | LILRB4,PPP3R1,TNFRSF11B,CSF1R,TGFB1,NFATC1,MAPK1,CALCR,STAT1,IL1B |
| Leishmaniasis | HLA-DQA1,PTGS2,FCGR2A,IL12A,HLA-DQA2,NFKB1,HLA-DPA1,FCGR1A,FCGR3A,CYBA |
| Phagosome | MHC2DAB,TUBAL3,STX18,FCGR3A,THBS1,ATP6AP1B,HLA-DRB1,MRC1,Ctsl,CALR3B |
| Natural killer cell mediated cytotoxicity | IFNGR1,PPP3R1,SHC3,Ifna15,IFNA16,VAV3,MAP2K1,ULBP1,KLRD1,IFNB1 |
| Systemic lupus erythematosus | HIST1H4D,HIST1H2AL,ACTN3,H3F3B,TRIM21,HIST1H3D,HIST2H4,H2AFY,FCGR3,HIST3H3 |
| Tuberculosis | PPP3CA,HLA-DRB1,SPHK2,IFNA10,NFYC,KSR1,PMAP-36,IL12A,SYK,IFNA2 |
| Staphylococcus aureus infection | C3,FCGR1A,CFH,HLA-DQA2,FCGR1,C4A,PTAFR,PLG,HLA-DMB,HLA-DQB1 |
Protein Function
FCGR3B has several biochemical functions, for example, IgG binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR3B itself. We selected most functions FCGR3B had, and list some proteins which have the same functions with FCGR3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| IgG binding | FCER1G,FCGRT,FCGR3A,UMOD,PIP,FCGR2C,cgr2b,CD247L,FCGR2B,FCGR1 |
Interacting Protein
FCGR3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGR3B here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGR3B.
spoVR
Resources
Research Area
Fc ReceptorsITIM/ITAM Immunoreceptors and Related Molecules
Myeloid Lineage Markers
Natural Killer Cells (NK Cells) Markers
Natural Killer (NK) Cell CD Antigen
Granulocyte Markers
Inflammatory/Monocyte-derived Dendritic Cells
Neutrophils
gamma delta T Cells
Natural Killer T (NKT) Cells
CD Antigen (Dendritic Cell Lineage Markers)
CD Antigen (Granulocyte Markers)
CD Antigen (Neutrophils)
Macrophage Marker CD Antigen
Monocyte Marker CD Antigen
Other Monocytes/Macrophages CD Antigen
Rheumatoid arthritis Therapeutic Targets
Macrophage Markers
Monocyte Markers
Lymphoid Lineage Markers
Dendritic Cell ITIM/ITAM Immunoreceptors
Dendritic Cell Pathogen Recognition/Uptake
MDSC Phenotyping - Positive Markers
Related Services
Related Products
References
- Kongmaroeng, C; Kumkaen, K; et al. FCGR3B gene frequencies among ethnic Thai blood donors from a regional hospital in Eastern Thailand. TISSUE ANTIGENS 85:127-131(2015).
- Chen, JY; Wang, CM; et al. Association of FCGR3A and FCGR3B Copy Number Variations With Systemic Lupus Erythematosus and Rheumatoid Arthritis in Taiwanese Patients. ARTHRITIS & RHEUMATOLOGY 66:3113-3121(2014).
