EPHA7
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Official Full Name
Eph receptor A7 -
Overview
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically h -
Synonyms
EPHA7;Eph receptor A7;ephrin type-A receptor 7;Cek 11;Developmental kinase 1;EBK;EHK-3;EHK3;EK11;Embryonic brain kinase;EPH homology kinase 3;EPH-like kinase 11;EPHA7_HUMAN;Ephrin receptor Eph A7;Ephrin type A receptor 7;hEK11;MDK 1;Receptor protein tyrosine kinase HEK 11;Tyrosine protein kinase receptor EHK 3;mDK-1;OTTMUSP00000005091;OTTMUSP00000005092;OTTMUSP00000005093;OTTMUSP00000005094;Mdk1;Cek11
Recombinant Proteins
- Human
- Rat
- Mouse
- Zebrafish
- Chicken
- E.coli
- HEK293
- Mammalian cells
- Insect Cell
- Sf9 Insect Cell
- Mammalian Cell
- Wheat Germ
- Human Cell
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Fc
- His&GST
- Non
- His&Flag
- Flag
- His&Fc
- His&Fc&Avi
- Myc&DDK
Involved Pathway
EPHA7 involved in several pathways and played different roles in them. We selected most pathways EPHA7 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHA7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | KCNQ2,CHL1,CDC42,CXCR4,CLTB,CDK5R1B,EFNA3B,EPHB1,MARK3,LRRC4 |
Protein Function
EPHA7 has several biochemical functions, for example, ATP binding,GPI-linked ephrin receptor activity,axon guidance receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHA7 itself. We selected most functions EPHA7 had, and list some proteins which have the same functions with EPHA7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| axon guidance receptor activity | SEMA5A,EPHB1,ROBO1,ROBO2,EPHB3,GFRA3 |
| chemorepellent activity | SEMA3H,SEMA4B,SEMA6E,FLRT2,SLIT2,SEMA4D,EFNA5,SEMA3D,SEMA3FA,SEMA5B |
| GPI-linked ephrin receptor activity | EPHA3,EK1,EPHA4,EPHA8,EPHA5 |
| protein binding | NDP,ADCYAP1,POLI,ZC3H15,SSX3,ALDH18A1,HSPA4,DACT1,LAMP2,KEL |
| ATP binding | RAD51B,NLRC3,TK2,TOR2A,TAP1,ABCC6,ATP13A4,MAP2K4B,OASL1,PTK6B |
| ephrin receptor binding | EFNB2B,NTRK3,EFNA5,EFNB2A,Anks1,EFNA3,EFNA2A,EFNB3B,CDK5R1,CBL |
| protein tyrosine kinase activity | RET,FGFR1A,EPHB2B,ZAP70,PTK7A,MUSK,KIAA1804,LCK,NTRK3A,EK1 |
Interacting Protein
EPHA7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPHA7 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPHA7.
Efna1;EPHA2;ephopt;EPHA3;EFNA4;EFNA5;abl-tide;MLLT4;GNB1;ZNF267;MAP1LC3A;czc8004;linkable pd173955 analogue;bisindolylmaleimide iii;purvalanol b
Resources
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References
- Xue, CY; Chen, YQ; et al. EphB4 expression in pterygium is associated with microvessel density. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 7:4008-4015(2014).
- Oricchio, E; Wendel, HG; et al. Functional genomics lead to new therapies in follicular lymphoma. BLAVATNIK AWARDS FOR YOUNG SCIENTISTS 2012 1293:18-24(2013).
