Recombinant Human EPH Receptor A7, GST-tagged

• Cat.No.: EPHA7-697H
• Product Overview: Recombinant human EPH receptor A7 catalytic domain (aa 579-998) with a GST tag is expressed inInsect cells. Activated in vitro via auto-phosphorylation.

Specification

• Cat. No.: EPHA7-697H
• Description: Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
• Source: Insect cells.
• Concentration: 0.33 mg/ml.
• Molecular Weight: 76.7 kDa.
• Formulation: Liquid in 50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2mM DTT + 50% glycerol.
• Specific Activity: 110 nmole of phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2 μg/ml.
• Storage: Stable for 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• Protein length: 579-998 a.a.

Gene Information

• Gene Name: EPHA7 EPH receptor A7 [ Homo sapiens ]
• Synonyms:
  EPHA7; EPH receptor A7; EHK-3; EK11; EPH homology kinase 3; EPH-like kinase 11; Eph homology kinase-3; ephrin type-A receptor 7; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EHK3; EC 2.7.10.1
• Gene ID: 2045
• mRNA Refseq: NM_004440
• Protein Refseq: NP_004431
• MIM: 602190
• UniProt ID: Q15375
• Chromosome Location: 6q16.1
• Pathway: Axon guidance
• Function: ATP binding; nucleotide binding; protein binding; receptor activity; transferase activity; transmembrane-ephrin receptor activity