DNAJC3
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Official Full Name
DnaJ (Hsp40) homolog, subfamily C, member 3 -
Overview
p58IPK is an inhibitor of interferon-induced and double-stranded RNA-activated protein kinase (PKR). It physically interacts with PKR and inhibits its activation and activity (1). Influenza virus activates p58IPK and thus blocks the activity of PKR to rep -
Synonyms
DNAJC3;DnaJ (Hsp40) homolog, subfamily C, member 3;PRKRI;dnaJ homolog subfamily C member 3;HP58;P58;P58IPK;protein kinase inhibitor p58;protein kinase inhibitor of 58 kDa;interferon-induced, double-stranded RNA-activated protein kinase inhibitor
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- GST
- DDK
- Myc
- Avi
- Fc
- Flag
Involved Pathway
DNAJC3 involved in several pathways and played different roles in them. We selected most pathways DNAJC3 participated on our site, such as Protein processing in endoplasmic reticulum,Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | UBE2J1,UBE2G2,SSR3,PKZ,RRBP1B,LMAN2,HSPA4L,SEC13,CAPN1B,SEL1L |
| Influenza A | MAPK3,LOC780933,FASLG,BLB2,IFNB1,PRKCB,IL12A,IL6,IL12B,PIK3R1 |
Protein Function
DNAJC3 has several biochemical functions, for example, chaperone binding,misfolded protein binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC3 itself. We selected most functions DNAJC3 had, and list some proteins which have the same functions with DNAJC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | B4GALT1,FAM83A,TOM1L1,BORA,SFN,BAD,CD4,PPP1R12A,MAP2K7,JAK2 |
| protein kinase inhibitor activity | CISHB,SOCS9,SOCS1A,NCK1,TRIB1,DUSP19,SOCS6B,NPM1,SOCS3B,SOCS1B |
| chaperone binding | DNAJB2,H2-KE2,UBL4,PARK2,TIMM9,TFRC,DNAJA3A,UBL4A,DNAJA1,DNAJB6 |
| misfolded protein binding | HDAC6,EDEM1,F12,CLU,HSPA5,STUB1,SDF2L1,DNAJB9,DNAJC10,BAG6 |
Interacting Protein
DNAJC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC3.
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