BSG
-
Official Full Name
basigin (Ok blood group) -
Overview
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
BSG;basigin (Ok blood group);M6;OK;5F7;TCSF;CD147;EMMPRIN;basigin;CD147 antigen;OK blood group antigen;collagenase stimulatory factor;leukocyte activation antigen M6;extracellular matrix metalloproteinase inducer;tumor cell-derived collagenase stimulatory factor
Recombinant Proteins
- Mouse
- Human
- Rat
- Rhesus macaque
- Chicken
- Zebrafish
- Cynomolgus
- Mus musculus
- HEK293
- NS0
- Human Cells
- Mammalian Cells
- Wheat Germ
- E.coli
- CHO
- In Vitro Cell Free System
- Rabbit
- His
- Fc&His
- Non
- Fc
- GST
- hIgG4
- Avi&His
- His&T7
- Flag
- His&Myc
- DDK&Myc
- mFc
- His&SUMO
- Avi&Fc&His
Involved Pathway
BSG involved in several pathways and played different roles in them. We selected most pathways BSG participated on our site, such as Basigin interactions,Cell surface interactions at the vascular wall,Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with BSG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hemostasis | F13A1B,LOC100514666,HMG20B,KIF4A,DOCK6,KIF9,PRTN3,S100A10B,APOA1B,HBBE2 |
| Degradation of the extracellular matrix | CTSK,MMP12,ADAMTS8,TPSAB1,ADAM8A,MMP8,ADAMTS4,CTRB1,MMP10,BMP1B |
| Cell surface interactions at the vascular wall | GRB14,NADL1.1,SLC3A2A,ITGB1B.1,PPIA,MERTK,DOK2,SLC16A8,SLC7A10,TREM1 |
| Basigin interactions | SLC7A10,SLC7A11,SLC7A8A,SLC3A2B,PPIA,NADL1.1,SLC3A2A,SLC7A6,SLC16A1,SLC16A8 |
| Matrix Metalloproteinases | MMP28,MMP26,MMP27,MMP15,MMP19,MMP17,MMP12,TIMP4,MMP25,MMP8 |
| Extracellular matrix organization | MFAP5,CEACAM1,COL28A1D,MFAP4,COL25A1,FN1B,BMP1A,CEACAM8,COL15A1B,LRP4 |
| Integrin cell surface interactions | LOC100514666,COL13A1,COL23A1,COL16A1,ICAM4,F11R.2,COL9A1A,JAM2B,COMP,FBN1 |
| Metabolism | SCO1,SREBF2,NHLRC1,SLC25A10,ECI1,GPC5A,YAP1,SLC46A1,CYP2D6,CYP2K6 |
Protein Function
BSG has several biochemical functions, for example, mannose binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BSG itself. We selected most functions BSG had, and list some proteins which have the same functions with BSG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | P4HB,ESR1,FAM108A1,LILRB4,SYT17,LIN9,NDUFA9,ASTE1,TAF3,KIF5B |
| mannose binding | CD209,MBL2,MRC1,Acr,COLEC10,LMAN2L,DPM1,CD209B,CD209A,CD207 |
Interacting Protein
BSG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BSG here. Most of them are supplied by our site. Hope this information will be useful for your research of BSG.
RFXANK;Cdk1;Tubb4b;USP50;Haus4;Haus7;RANBP3;ATXN10;UBE2A;mviM6;dapF;PDLIM7;b3xyc5_sollc;cona_canen;ATF2;P
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References
- Saetear, P; Perrin, AJ; et al. Quantification of Plasmodium-host protein interactions on intact, unmodified erythrocytes by back-scattering interferometry. MALARIA JOURNAL 14:-(2015).
- Cabanas, R; Saurez, G; et al. Prolonged Use of Nimotuzumab in Children with Central Nervous System Tumors: Safety and Feasibility. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 29:173-178(2014).
