AMELX
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Official Full Name
Amelogenin, X-Linked -
Overview
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in;biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta.;Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
AMELX;AMG;AI1E;AIH1;ALGN;AMGL;AMGX;amelogenin, X isoform;amelogenesis imperfecta 1;amelogenin (amelogenesis imperfecta 1, X-linked);amelogenin (X chromosome, amelogenesis imperfecta 1)
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Yeast
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- Insect Cell
- GST
- His
- Non
- His&Fc&Avi
- His&Myc
- His&SUMO
Involved Pathway
AMELX involved in several pathways and played different roles in them. We selected most pathways AMELX participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMELX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AMELX has several biochemical functions, for example, growth factor activity,hydroxyapatite binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMELX itself. We selected most functions AMELX had, and list some proteins which have the same functions with AMELX. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydroxyapatite binding | BGLAP,PTPLA,BGLAP2,STATH,HTN1 |
| protein binding | LEO1,RPL37A,RABGEF1,ATG4B,MMRN2,PDCD6IP,SULT2A1,CCL4,AXL,VAPB |
| structural constituent of tooth enamel | STATH,TUFT1,AMELY,AMBN |
| identical protein binding | GCC2,MAP1S,IFI16,CEACAM16,NLRC4,DYNLT1,POLG2,BNIP3,JMJD6,SHARPIN |
| growth factor activity | CD320,LEFTY1,LEP,INHBAB,CXCL12,FGF16,INHBE,IL34,FGF7,NODAL |
Interacting Protein
AMELX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMELX here. Most of them are supplied by our site. Hope this information will be useful for your research of AMELX.
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