Recombinant Human AMELX, His-tagged

• Cat.No.: AMELX-7077H
• Product Overview: Recombinant human AMELX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: AMELX is a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in AMELX cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl,30% glycerol, 1mM DTT
• Molecular Mass: 22 kDa (198aa)
• Protein length: 17-191aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPLPPHP GHPGYINFSY EVLTPLKWYQ SIRPPYPSYG YEPMGGWLHH QIIPVLSQQH PPTHTLQPHHHIPVVPAQQP VIPQQPMMPV PGQHSMTPIQ HHQPNLPPPA QQPYQPQPVQ PQPHQPMQPQ PPVHPMQPLP PQPPLPPMFP MQPLPPMLPD LTLEAWPSTD KTKREEVD
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: AMELX amelogenin, X-linked [ Homo sapiens ]
• Official Symbol: AMELX
• Synonyms: AMELX; amelogenin, X-linked; AIH1, amelogenin (X chromosome, amelogenesis imperfecta 1) , AMG; amelogenin, X isoform; amelogenesis imperfecta 1; amelogenin (amelogenesis imperfecta 1, X-linked); amelogenin (X chromosome, amelogenesis imperfecta 1); AMG; AI1E; AIH1; ALGN; AMGL; AMGX
• Gene ID: 265
• mRNA Refseq: NM_001142
• Protein Refseq: NP_001133
• MIM: 300391
• UniProt ID: Q99217
• Chromosome Location: Xp22.31-p22.1
• Function: cell surface binding; growth factor activity; hydroxyapatite binding; identical protein binding; protein binding; structural constituent of tooth enamel; structural constituent of tooth enamel