SPINT1
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Official Full Name
serine peptidase inhibitor, Kunitz type 1 -
Overview
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008] -
Synonyms
SPINT1;serine peptidase inhibitor, Kunitz type 1;HAI;HAI1;MANSC2;kunitz-type protease inhibitor 1;HAI-1;serine protease inhibitor, Kunitz type 1;hepatocyte growth factor activator inhibitor type 1
Recombinant Proteins
- Human
- Mouse
- HEK293
- E.coli
- Mammalian cells
- Mammalian Cell
- Wheat Germ
- Human Cell
- In Vitro Cell Free System
- HEK293T
- His
- Fc
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SPINT1 involved in several pathways and played different roles in them. We selected most pathways SPINT1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPINT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | MLF1,TLX3,PDGFA,PPARG,TRP53,HOXA9,PER2,FLT3,ID2,MEN1 |
Protein Function
SPINT1 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPINT1 itself. We selected most functions SPINT1 had, and list some proteins which have the same functions with SPINT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase inhibitor activity | SPINK3,WFDC6A,PI3,SPINK10,SPINK12,Serpina1b,SERPINA1D,SPINK13,SERPINE3,APPB |
Interacting Protein
SPINT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPINT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPINT1.
HGFAC;FAM46A;UBQLN4
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