SETD7
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Official Full Name
SET domain containing (lysine methyltransferase) 7 -
Overview
Histone-lysine N-methyltransferase SETD7 is an enzyme that in humans is encoded by the SETD7 gene. -
Synonyms
SETD7;SET domain containing (lysine methyltransferase) 7;histone-lysine N-methyltransferase SETD7;KIAA1717;KMT7;SET7;SET7/9;Set9;H3-K4-HMTase SETD7;lysine N-methyltransferase 7;SET domain-containing protein 7;histone H3-K4 methyltransferase SET
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Sf9 Insect Cell
- Mammalian Cell
- HEK293
- E. coli
- HEK293T
- GST
- His
- His&GST
- T7
- Non
- Myc&DDK
- His&Fc&Avi
- His&Myc&SUMO
Involved Pathway
SETD7 involved in several pathways and played different roles in them. We selected most pathways SETD7 participated on our site, such as Lysine degradation,FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | ALDH1B1,GLT25D2,HYKK,GCDHB,PLOD3,PLOD1,SETDB1B,SETMAR,PIPOX,ACAT2 |
| FoxO signaling pathway | CDKN2D,G6PC2,PLK2,AGAP2,PRKAA1,IRS1,SIRT1,HOMER1,PIK3R1,MAPK12A |
Protein Function
SETD7 has several biochemical functions, for example, chromatin binding,histone-lysine N-methyltransferase activity,p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD7 itself. We selected most functions SETD7 had, and list some proteins which have the same functions with SETD7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein-lysine N-methyltransferase activity | METTL8,DIMT1,METTL21C,PRDM12,EZH2,NDUFAF5,TRMT10B,SMYD2B,PRMT8B,PRDM13 |
| p53 binding | RFFL,TP63,ZFP385C,EHMT2,SETD8,BANP,TRIM29,TAF1,MAPKAPK5,AXIN1 |
| protein binding | PPP6R2,CCL28,PTCH1,CCDC41,LRP4,ENTPD1,LIG3,NAE1,ZFPM2A,NAT2 |
| chromatin binding | PLAC8,CDK9,NAP1L2,MB21D2,GABPA,MLL1,SMC1AL,SKIL,PHC1,RBPJL |
| histone-lysine N-methyltransferase activity | AAAS,SMYD1,SETD2,SETD8,SETD8A,MLL1,EZH1,EZH2,SMYD2A,PRDM2 |
Interacting Protein
SETD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD7.
TP53;HIST1H3D;RELA
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