SERPINF1
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Official Full Name
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -
Overview
The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011] -
Synonyms
SERPINF1;serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1;OI6;OI12;PEDF;EPC-1;PIG35;pigment epithelium-derived factor;serpin F1;cell proliferation-inducing gene 35 protein;serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Chicken
- Cynomolgus
- Rat
- Cattle
- Bovine
- HEK293
- Mammalian cells
- E.coli
- Mammalian Cell
- CHO
- Human Cell
- Rabbit
- Baculovirus-Infected Sf9 Cells
- HEK293T
- His
- Non
- Flag
- Myc&DDK
- His&SUMO
- His&Fc&Avi
- GST
- N-His&C-Myc
Involved Pathway
SERPINF1 involved in several pathways and played different roles in them. We selected most pathways SERPINF1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | PRKCA,FOSL1A,WNT7B,FBXW11B,MYCB,GSK3AA,WNT2,NKD2B,VANGL1,FRAT2 |
Protein Function
SERPINF1 has several biochemical functions, for example, protein binding,serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINF1 itself. We selected most functions SERPINF1 had, and list some proteins which have the same functions with SERPINF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase inhibitor activity | FURIN,WFDC12,PZP,SLPI,A1i3,SERPINA3C,SERPINA5,WFDC6A,AGT,WFDC13 |
| protein binding | ZBTB8A,KRT5,BBS12,Clec4n,NCOA2,RRP7A,CXCL14,DNAJC5B,UBE2K,MTAP1B |
Interacting Protein
SERPINF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINF1.
EPM2AIP1;ATP1;ATP15;ATP2;ATP3;ATP16;MLH1
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