PPA1

  • Official Full Name

    pyrophosphatase (inorganic) 1

  • Overview

    The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the;hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies;of a similar protein in bovine suggested a cytoplasmic localization of this enzyme.

  • Synonyms

    PPA1;pyrophosphatase (inorganic) 1;PP, pyrophosphatase (inorganic);inorganic pyrophosphatase;cytosolic inorganic pyrophosphatase;inorganic pyrophosphatase 1;IOPPP;PP1;Ppase;pyrophosphate phospho hydrolase;SID6 8061;pyrophosphatase 1;in

Recombinant Proteins

  • Human
  • Cynomolgus
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • T7
  • Non
  • Flag
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    PPA1 involved in several pathways and played different roles in them. We selected most pathways PPA1 participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation ATP6V1B2,UQCRH,ATP5F1,ATP5G3,NDUFS8,ATP5D,NDUFB7,COX7A2A,NDUFS8B,NDUFA2

    Protein Function

    PPA1 has several biochemical functions, for example, inorganic diphosphatase activity,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPA1 itself. We selected most functions PPA1 had, and list some proteins which have the same functions with PPA1. You can find most of the proteins on our site.

    Function Related Protein
    inorganic diphosphatase activity PPA2,PPA1B,PPA1A,PRUNE,LHPP
    magnesium ion binding PKM,DXO,ENO1,HPRT1L,TSSK4,FIGNL1,IMPA2,ATP8B5,STK11,PSPH

    Interacting Protein

    PPA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPA1.

    TP53;HSPB1;UNC119;SETDB1;WIPI1;MAPK13;GABARAP;VCAM1;MAP1LC3A

    Resources

    Research Area

    Phosphatases and Regulators

    References

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    Q&As

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