GREM1
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Official Full Name
Grem1 gremlin 1 -
Synonyms
GREM1;gremlin 1;gremlin-1;down-regulated in v-mos-transformed cells;cysteine knot superfamily 1, BMP antagonist 1;down-regulated in Mos-transformed cells protein;ld;Drm;Grem;Cktsf1b1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian cells
- CHO
- Insect Cell
- HEK293
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Fc
- His&Fc&Avi
- His&Myc
- His&SUMO
Involved Pathway
GREM1 involved in several pathways and played different roles in them. We selected most pathways GREM1 participated on our site, such as BMP receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GREM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| BMP receptor signaling | FST,AHSG,RGMA,CTDSP2,CTDSP1,SOSTDC1,CTDSPL,RGMB,HFE2,CALML4 |
Protein Function
GREM1 has several biochemical functions, for example, BMP binding,cytokine activity,morphogen activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GREM1 itself. We selected most functions GREM1 had, and list some proteins which have the same functions with GREM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IFNA4,AIMP1,IL21,GPI1,IL31,IFNA14,TNFRSF11B,Ifna15,BMP8A,TGFB1 |
| BMP binding | GDF5,BMPR2,TCAP,CER1,HFE2,GREM2,NBL1 |
| transmembrane receptor protein tyrosine kinase activator activity | EFNA5,NRG1,ANGPT4,NRG3,EGF |
| morphogen activity | NODAL,DAND5,CER1,Shh,NBL1 |
| receptor agonist activity | WNT7A,WNT4,WNT2,CXCL13,WNT3A,WNT10B,WNT5A,GAS6,NODAL,WNT1 |
| vascular endothelial growth factor receptor 2 binding | ITGB3,VEGFA,PDCL3,ITGA5 |
| protein binding | HSD3B7,MLH1,KIRREL,LONRF3,CIB2,ZFPM2A,PML,CD244,CHERP,SNRPE |
Interacting Protein
GREM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GREM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GREM1.
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