ERN1
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Official Full Name
endoplasmic reticulum to nucleus signaling 1 -
Synonyms
ERN1;endoplasmic reticulum to nucleus signaling 1;ER to nucleus signalling 1;serine/threonine-protein kinase/endoribonuclease IRE1;inositol requiring enzyme 1;IRE1;IRE1P;ire1-alpha;inositol-requiring 1;inositol-requiring enzyme 1;inositol-requir
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Insect Cell
- Insect cell
- E.coli
- Mammalian Cell
- Wheat Germ
- Insect cells
- Sf9 insect cells
- Baculovirus-Insect cells
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- Fc
- GST
- His
- Non
- N-GST-His
- His&Avi
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
ERN1 involved in several pathways and played different roles in them. We selected most pathways ERN1 participated on our site, such as Protein processing in endoplasmic reticulum,Non-alcoholic fatty liver disease (NAFLD),Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Non-alcoholic fatty liver disease (NAFLD) | PRKAG3,NDUFC2-KCTD14,NDUFA12,NDUFS7,CYCS,Casp3,LEPR,SDHB,NDUFA10,NDUFA6 |
| Alzheimers disease | SDHA,mt-Atp8,NDUFV3,COX7A2,AKR1C1,COX6A2,NDUFA10,CALM4,NDUFA1,UQCR10 |
| Protein processing in endoplasmic reticulum | BCL2A,CUL1,SEL1L2,SEC63,PPP1R15A,UBQLNL,CUL1A,NSFL1C,SEC23B,CALR |
Protein Function
ERN1 has several biochemical functions, for example, ADP binding,ATP binding,Hsp70 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERN1 itself. We selected most functions ERN1 had, and list some proteins which have the same functions with ERN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | RAG1,TBX18,CD8A,CHEK2,PRKG2,SP100,NDP,FLNA,CITED1,RNF40 |
| protein serine/threonine kinase activity | RAF1B,DYRK2,WNK1,MKNK1,RPS6KB2,STK38L,MAPK8A,CAMK2B1,STK39,MAP3K8 |
| Hsp70 protein binding | L7RN6,DNAJA1,FAM119A,CDK1,STUB1,PPEF2,MVD,DNAJB2,PPID,CDKN1B |
| protein binding | BCCIP,JMJD6,ASB13,PPP2R5D,RAB6A,HEYL,ATP5F1,SAMM50,PARP16,NDUFA13 |
| ADP binding | MYH10,PRKAG2,LONP1,HSP104,VCP,MYH9,CHORDC1,ATP1A1,ACTA1,CYB5R3 |
| endoribonuclease activity | SMG6,RNASEKB,RNASEKA,ENDOU2,AGO2,RCL1,DICER1,CPSF3,RNASET2,NOB1 |
| Hsp90 protein binding | PPEF2,UNC45A,NASP,PACRG,USP19,CDC37,AHR,ARNTL,GBP1,FKBP6 |
| ATP binding | DDX18,DCAMKL2,BCKDK,MAP2K6,ATPBD4,PTK2AA,EGFRA,PHKG1A,SARS2,AURKC |
| identical protein binding | CALHM1,MDM2,DESI1,IIGP1,CAV1,PLDN,VEGFA,FBLN1,EED,IGF1R |
Interacting Protein
ERN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERN1.
N/A;TRAF2;Bax;SYVN1;TAOK3;s2;SRPK2;BAX;Bak1;HSPA5
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References
- Huu, NT; Yoshida, H; et al. Structural characterization and subcellular localization of Drosophila organic solute carrier partner 1. BMC BIOCHEMISTRY 15:-(2014).
- Deliu, E; Brailoiu, GC; et al. Direct evidence of intracrine angiotensin II signaling in neurons. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 306:C736-C744(2014).
