DEFB1
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Official Full Name
defensin, beta 1 -
Overview
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. -
Synonyms
beta 1;BD 1;BD-1;BD1;Beta defensin 1;Beta-defensin 1;DEFB 1;DEFB1;DEFB1_HUMAN;DEFB101;Defensin;Defensin beta 1;Defensin beta 1 preproprotein;HBD 1;hBD-1;HBD1;MGC51822
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Chicken
- Cattle
- Pig
- E.coli
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- Non
- His
- Myc&DDK
- Fc
- His&GST
- His&S
- His&Fc&Avi
- His&SUMO
Involved Pathway
DEFB1 involved in several pathways and played different roles in them. We selected most pathways DEFB1 participated on our site, such as Beta defensins,Defensins,Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with DEFB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | DYNC1I2,RNF123,IFIT3,KIF5A,FAM49BA,POLR3H,PVRL2L,OSBPL1A,SH2D1B,CLEC2G |
| Innate Immune System | TAX1BP1B,KIR2DS2,CRP,POLR3F,SUGT1,BTR12,DEFB106A,CTSLL,RIPK3,BAIAP2 |
| Defensins | DEFA3,DEFB119,DEFB125,DEFB103A,DEFA5,DEFB106A,DEFA1,DEFB116,DEFB4A,DEFB129 |
| Beta defensins | CCR6,DEFB4B,DEFB125,DEFB116,DEFB106A,DEFB104A,DEFB103A,DEFB129,DEFB119,DEFB121 |
Protein Function
DEFB1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DEFB1 itself. We selected most functions DEFB1 had, and list some proteins which have the same functions with DEFB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
DEFB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEFB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DEFB1.
RhoA;MAP4K2
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References
