Recombinant Human DEFB1

• Cat.No.: DEFB1-27203TH
• Product Overview: Recombinant Human beta-Defensin 1, a 3.9 kDa protein containing 36 amino acid residues.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
• Tissue specificity: Plasma.
• Biological activity: Biological Activity : Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml.
• Form: Lyophilised
• Purity: >95% by SDS-PAGE
• Storage: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
• Sequences of amino acids: DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK
• Sequence Similarities: Belongs to the beta-defensin family.

Gene Information

• Gene Name: DEFB1 defensin, beta 1 [ Homo sapiens ]
• Official Symbol: DEFB1
• Synonyms: DEFB1; defensin, beta 1; beta-defensin 1; DEFB 1; DEFB101; HBD 1; HBD1
• Gene ID: 1672
• mRNA Refseq: NM_005218
• Protein Refseq: NP_005209
• MIM: 602056
• Uniprot ID: P60022
• Chromosome Location: 8p23.1