Cma1
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Official Full Name
chymase 1, mast cell -
Overview
Monocyte chemotactic protein 5 (MCP-5);, also known as CCL 12, is a novel and potent monocyte active chemokine that is involved in allergic inflammation and the host response to pathogens.1 It is also a potent chemoattractant for peripheral blood monocyte -
Synonyms
CMA1;chymase 1, mast cell;chymase;alpha-chymase;mast cell chymase 1;mast cell protease 5;mast cell protease I;Mcp5;Mcp-5;Mcpt5;MMCP-5
Recombinant Proteins
- Human
- Mouse
- Rat
- Cynomolgus
- Rhesus macaque
- Dog
- E.coli
- Mammalian Cells
- P.pastoris
- Human Skin
- Wheat Germ
- Insect Cells
- HEK293
- Yeast
- In Vitro Cell Free System
- GST
- His&GST
- His
- Non
- His&Fc&Avi
- His&SUMO
Involved Pathway
Cma1 involved in several pathways and played different roles in them. We selected most pathways Cma1 participated on our site, such as ACE Inhibitor Pathway,Activation of Matrix Metalloproteinases,Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cma1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Activation of Matrix Metalloproteinases | TIMP2A,MMP13,MGC174857,FURINA,FURINB,ELANE,MMP17,CTSG,CTRB1,TIMP2 |
| ACE Inhibitor Pathway | ATP6AP2,CYP11B2,AGTR1,AGTR2,ACE,AGT,CTSG |
| Peptide hormone metabolism | GPR119,ATP6AP2,ACE,SLC30A8,CPB2,CPB1,INHBAA,CGB5,CPA3,CGB7 |
| Degradation of the extracellular matrix | LOC100686744,TIMP2A,COL19A1,TLL1,CTSL1,ADAM8,TIMP2B,ADAM8A,FURINB,CAPNS1 |
| Metabolism of proteins | DNAJB9,PFDN1,MUCL1,MUC4,ST8SIA2,SPON1A,NAT8,TRAPPC2L,DCP2,THSD1 |
| Renin-angiotensin system | THOP1,PRCP,Ren1,KLK1B11,ACE,CPA3,KLK1B3,CTSA,ACE2,KLK1B8 |
| Metabolism of Angiotensinogen to Angiotensins | ATP6AP2,CTSG,CPB2,ACE,CPB1,GZMH,CPA3 |
| Extracellular matrix organization | TIMP2A,LTBP3,COL5A3A,CTRB1,ADAM8,COL28A1,EFEMP2,FAM49BA,FBLN2,ADAMTS4 |
Protein Function
Cma1 has several biochemical functions, for example, peptide binding,serine-type endopeptidase activity,serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cma1 itself. We selected most functions Cma1 had, and list some proteins which have the same functions with Cma1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type peptidase activity | OVCH2,ELA2L,DPP9,KLK11,KLK4,PRSS28,PRSS52,MCPT2,HTRA1B,DPP6 |
| peptide binding | GNRHR1,MAS1,NPFFR1,ANPEPB,GNRHR2,GPR37,ADNP,TPP1,CRHBP,PPYR1 |
| serine-type endopeptidase activity | ELANE,PCSK9,TMPRSS11G,CELA2A,LONP1,GZMK,TMPRSS2,PRSS58,FAP,ELA3L |
Interacting Protein
Cma1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cma1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cma1.
Resources
Research Area
Serine Proteases and RegulatorsInflammatory Mediators
Granulocyte Markers
Mast Cells
CD Antigen (Granulocyte Markers)
Related Services
Related Products
References
