ACVR1B
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Official Full Name
activin A receptor, type 1B -
Overview
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a hete -
Synonyms
ACVR1B;activin A receptor, type 1B;activin receptor type-1B;ALK-4;activin receptor type IB;activin receptor-like kinase 4;serine/threonine-protein kinase receptor R2;Alk4;SKR2;ActRIB;ActR-IB;Acvrlk4;6820432J04
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Cynomolgus
- HEK293
- Human Cells
- Mammalian Cells
- Insect Cells
- E.coli
- Sf9 Cells
- Wheat Germ
- BTI Insect Cell
- In Vitro Cell Free System
- His
- Fc&His
- Fc
- Non
- GST
- GST&His
- Avi&Fc&His
Involved Pathway
ACVR1B involved in several pathways and played different roles in them. We selected most pathways ACVR1B participated on our site, such as Cytokine-cytokine receptor interaction,TGF-beta signaling pathway,Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACVR1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | GM13304,IL2RB,Ccl9,CXCL10,EPO,TNF,TNFSF9,TNFRSF9,IL21R,CCR6A |
| Signaling pathways regulating pluripotency of stem cells | NRAS,SKIL,IL6ST,ID3,WNT7A,FZD3,WNT9A,ACVR2B,WNT2B,PIK3R3 |
| TGF-beta signaling pathway | CUL1B,SP1,ROCK2B,ID2B,PPP2CB,TGFB1,TGFB1A,ZFYVE9,BMPR2A,INHBE |
Protein Function
ACVR1B has several biochemical functions, for example, ATP binding,SMAD binding,contributes_to activin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACVR1B itself. We selected most functions ACVR1B had, and list some proteins which have the same functions with ACVR1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | MYCBP2,ZC3H14,ZNF280D,DMRTC2,THAP6,COLEC12,ERMP1,GNAO1,SMYD4,ZNF576.2 |
| transmembrane receptor protein serine/threonine kinase activity | BMPR1BA,BMPR2B,BMPR1A,ACVR2AA,BMPR1BB,ALPK2,TGFBR1A,BMPR2A,ACVR1BA,TGFBR2 |
| activin receptor activity, type I | ACVR1C,ACVRL1 |
| inhibin binding | INHA,ACVR2A,INHBA,IGSF1 |
| protein binding | AHNAK,INS,MAP1LC3B,FAM206A,TBX24,SMCR7,CDIPT,PDE6H,MAP3K8,SPEF2 |
| contributes_to activin binding | ACVR2A |
| contributes_to activin-activated receptor activity | ACVR2A |
| contributes_to growth factor binding | ERBB2,TGFBR1,IL6ST |
| ATP binding | KIF5A,ATP2A1L,ABCD3B,PDXK,RPS6KA3A,PSTK,AK9,LIMK1A,RTCD1,DDX24 |
Interacting Protein
ACVR1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACVR1B here. Most of them are supplied by our site. Hope this information will be useful for your research of ACVR1B.
SMAD7;HSP90AB1;FKBP1A;XIAP;RXRA;PRKACB;BAG6;OS9;bosutinib
Resources
Research Area
Embryonic and Induced Pluripotent Stem Cell MarkersActivin Receptor
TGF-beta Family Receptor
Related Services
Related Products
References
