RepSox, GMP Grade
| Cat.No. : | RepSox-21 |
| Product Overview : | RepSox (E-616452) (GMP) is a RepSox produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. |
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| Description : | RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor. |
| Form : | Solid, White to light yellow |
| Target : | TGF-β Receptor |
| In Vitro : | RepSox (GMP) (10 μM) induces MEFs differentiating to chemically induced pluripotent stem cells (CiPSCs). RepSox (GMP) (10 μM, in stage I-Stage III induction medium) induces hCiPS cells from HEFs. RepSox (GMP) together with Forskolin increases the number of proliferative cells in MEFs expressing MyoD, confirmed by increased EdU incorporation |
| IC50 & Target : | IC50: ALK5 autophosphorylation (4 nM) |
| CAS : | 446859-33-2 |
| Formula : | C17H13N5 |
| Molecular Mass : | 287.32 |
| Storage : | 4 centigrade, sealed storage, away from moisture and light |
| Pathway | TGF-beta/Smad |
| Official Symbol | RepSox |
| Synonyms | RepSox; E-616452; SJN 2511 |
| ◆ Recombinant Proteins | ||
| RepSox-21 | RepSox, GMP Grade | +Inquiry |
Not For Human Consumption!
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