Recombinant Zebrafish tek Protein, His&GST-tagged

• Cat.No.: tek-1257Z
• Product Overview: Recombinant Zebrafish tek Protein (Val22-Ala312) with His&GST tag was expressed in E. coli.

Specification

• Description: Predicted to enable transmembrane receptor protein tyrosine kinase activity. Acts upstream of or within angiogenesis and heart development. Predicted to be located in several cellular components, including cytoskeleton; focal adhesion; and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in endothelial cell; vasculature; and vertical myoseptum. Human ortholog(s) of this gene implicated in arteriovenous malformation and multiple cutaneous and mucosal venous malformations. Orthologous to human TEK (TEK receptor tyrosine kinase).
• Source: E. coli
• Species: Zebrafish
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 61.3 kDa; Accurate Molecular Mass: 61 kDa
• Protein length: Val22-Ala312
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: tek TEK tyrosine kinase, endothelial [ Danio rerio (zebrafish) ]
• Official Symbol: tek
• Synonyms: tek; TEK tyrosine kinase, endothelial; tie2; tie-2; tyrosine-protein kinase receptor Tie-2; endothelium-specific receptor tyrosine kinase 2; tyrosine kinase with Ig and EGF homology domains-2; EC 2.7.10.1
• Gene ID: 30747
• mRNA Refseq: NM_131461
• Protein Refseq: NP_571536
• UniProt ID: O73791