Recombinant Saccharomyces cerevisiae SNF2 Protein, His-tagged

• Cat.No.: SNF2-74S
• Product Overview: Recombinant Saccharomyces cerevisiae SNF2 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: Enables several functions, including ATP-dependent chromatin remodeler activity; DNA binding activity; and lysine-acetylated histone binding activity. Involved in several processes, including DNA metabolic process; nucleosome mobilization; and positive regulation of cell adhesion involved in single-species biofilm formation. Located in nucleus. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid cancer. Orthologous to human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) and SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4).
• Source: E. coli
• Species: Saccharomyces cerevisiae
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4).
• Molecular Mass: ~91 kDa
• AA Sequence: MKIEEGKLVIWINGDKGYNGLAEVG KKFEKDTGIKVTVEHPDKLEEKFPQ VAATGDGPDIIFWAHDRFGGYAQSG LLAEITPDKAFQDKLYPFTWDAVRY NGKLIAYPIAVEALSLIYNKDLLPN PPKTWEEIPALDKELKAKGKSALMF NLQEPYFTWPLIAADGGYAFKYENG KYDIKDVGVDNAGAKAGLTFLVDLI KNKHMNADTDYSIAEAAFNKGETAM TINGPWAWSNIDTSKVNYGVTVLPT FKGQPSKPFVGVLSAGINAASPNKE LAKEFLENYLLTDEGLEAVNKDKPL GAVALKSYEEELAKDPRIAATMENA QKGEIMPNIPQMSAFWYAVRTAVIN AASGRQTVDEALKDAQTIEGRMNGI LADEMGLGKTIQTISLLTYLYEMKN IRGPYLVIVPLSTLSNWSSEFAKWA PTLRTISFKGSPNERKAKQAKIRAG EFDVVLTTFEYIIKERALLSKVKWV HMIIDEGHRMKNAQSKLSLTLNTHY HADYRLILTGTPLQNNLPELWALLN FVLPKIFNSVKSFDEWFNTPFANTG GQDKIELSEEETLLVIRRLHKVLRP FLLRRLKKDVEKELPDKVEKVVKCK MSALQQIMYQQMLKYRRLFIGDQNN KKMVGLRGFNNQIMQLKKICNHPFV FEEVEDQINPTRETNDDIWRVAGKF ELLDRILPKLKATGHRVLIFFQMTQ IMDIMEDFLRYINIKYLRLDGHTKS DERSELLRLFNAPDSEYLCFILSTR AGGLGLNLQTADTVIIFDTDWNPAQ ALQAQDRAHRIGQKNEVRILHHHHH H
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.1 mg/ml
• Official Full Name: SWI/SNF catalytic subunit SNF2

Gene Information

• Gene Name: SNF2 SWI/SNF catalytic subunit SNF2 [ Saccharomyces cerevisiae S288C ]
• Official Symbol: SNF2
• Synonyms: GAM1; HAF1; SWI2; TYE3
• Gene ID: 854465
• mRNA Refseq: NM_001183709
• Protein Refseq: NP_014933
• UniProt ID: P22082