Recombinant Rhesus macaque SLAMF7 protein, His-tagged

• Cat.No.: SLAMF7-353R
• Product Overview: Recombinant Rhesus macaque SLAMF7 protein (Ser23-Met226), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293).

Specification

• Species: Rhesus macaque
• Source: HEK293
• Tag: His
• Protein Length: 204
• Description: SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
• Form: Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 24.4 kDa. The protein migrates as 35-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU per ug by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 centigrade to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: SLAMF7
• Official Symbol: SLAMF7
• Synonyms: 19A; CD319; CRACC; CS1
• Gene ID: 719781
• mRNA Refseq: XM_001117618.4
• Protein Refseq: XP_001117618.2
• UniProt ID: F7HQ72