Description :	Predicted to enable copper ion binding activity; protein homodimerization activity; and tyrosinase activity. Involved in several processes, including response to UV; response to cAMP; and response to vitamin D. Located in cytosol and nucleus. Used to study oculocutaneous albinism. Human ortholog(s) of this gene implicated in melanoma (multiple); ocular albinism; oculocutaneous albinism (multiple); retinoschisis; and vitiligo. Orthologous to human TYR (tyrosinase).
Source :	E. coli
Species :	Rat
Tag :	His
Form :	Freeze-dried powder
Molecular Mass :	Predicted Molecular Mass: 43.7 kDa Accurate Molecular Mass: 38 kDa
Protein length :	Ile233-Leu530
Purity :	> 90%
Applications :	Positive Control; Immunogen; SDS-PAGE; WB.
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer :	PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
Reconstitution :	Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Name	Tyr tyrosinase [ Rattus norvegicus (Norway rat) ]
Official Symbol	Tyr
Synonyms	Tyr; tyrosinase; EC 1.14.18.1
Gene ID	308800
mRNA Refseq	NM_001107535
Protein Refseq	NP_001101005
UniProt ID	D4A9G4