Recombinant Rat Thbd Protein, His-tagged

• Cat.No.: Thbd-425R
• Product Overview: Recombinant Rat Thbd Protein (Ile17-Gly518) with N-His tag was expressed in 293F.

Specification

• Species: Rat
• Source: HEK293
• Tag: His
• ProteinLength: Ile17-Gly518
• Description: Predicted to enable calcium ion binding activity and transmembrane signaling receptor activity. Involved in response to X-ray; response to cAMP; and response to lipopolysaccharide. Located in apicolateral plasma membrane; extracellular space; and vacuolar membrane. Used to study acute kidney failure. Biomarker of adult respiratory distress syndrome; hypertension; ischemia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 55.4 kDa
  Accurate Molecular Mass: 100 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Thbd thrombomodulin [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Thbd
• Synonyms: THBD; thrombomodulin; TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12; thrombomodulin; CD141 antigen; fetomodulin
• Gene ID: 83580
• mRNA Refseq: NM_031771
• Protein Refseq: NP_113959
• UniProt ID: O35370