Recombinant Rat Protein Arginine Methyltransferase 1

• Cat.No.: Prmt1-711R
• Product Overview: Recombinant Rat protein arginine methyltransferase 1 was expressed inE Coli.

Specification

• Cat. No.: Prmt1-711R
• Description: PRMT1 is the predominant member of the methyl transferases, which catalyzes the protein arginine N-methylation reactions. PRMT1 is implicated in various cellular processes including: transcription, RNA processing, and signal transduction. The N-methyltransferase activity is determined by detecting the level of radiolabel transfer from 3H-AdoMet (Methyl donor) to histone, which is arginine rich (methyl acceptor). Actions Methyl transferases catalyze the addition of methyl groups to nitrogen, carbon, sulfur, and oxygen atoms of small molecules, lipids, proteins, and nucleic acids. Eight mammalian protein arginine methyltransferases (PRMT) have been identified.
• Source: E Coli.
• Unit Definition: The specific activity is ≥ 0.1 nmol/mgP/min. measured by 3H-AdoMet incorporation into histone for 30 minues at 30℃.
• Physical Form: Solution of 50 mM Tris, pH 7.6, 5 mM DTT, 0.2% IGEPAL® CA-630, 150 mM NaCl, and 30% glycerol (w/v).
• Legal Information: IGEPAL is a registered trademark of Rhodia Operations.
• Assay: ≥90% (SDS-PAGE).
• Form: Buffered aqueous solution.
• Shipped in: Dry ice.
• Storage temp: −20℃.
• Personal Protective Equipment: Eyeshields,Gloves,half-mask respirator (EU),half-mask respirator (US),multi-purpose combination respirator cartridge (US).
• Tag: Non

Gene Information

• Gene Name: Prmt1 protein arginine methyltransferase 1 [ Rattus norvegicus ]
• Synonyms: Prmt1; protein arginine methyltransferase 1; Hrmt1l2; protein arginine N-methyltransferase 1; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2
• Gene ID: 60421
• mRNA Refseq: NM_024363
• Protein Refseq: NP_077339
• UniProt ID: Q63009
• Chromosome Location: 1q22
• Function: S-adenosylmethionine-dependent methyltransferase activity; [cytochrome c]-arginine N-methyltransferase activity; histone-arginine N-methyltransferase activity; protein binding; protein methyltransferase activity; protein methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; snoRNP binding; transferase activity