Recombinant Rat PDCD1 Protein, Fc-tagged

• Cat.No.: PDCD1-704R
• Product Overview: Recombinant Rat PDCD1 protein with Fc tag was expressed in HEK293.

Specification

• Description: Predicted to be involved in negative regulation of immune response and positive regulation of T cell apoptotic process. Predicted to act upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in plasma membrane. Biomarker of anti-basement membrane glomerulonephritis; periodontitis; and pre-eclampsia. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1).
• Source: HEK293
• Species: Rat
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 42.9 kDa
• Protein length: 287
• AA Sequence: MWVQQVPWSFTWAVLQLSWQSGWLLEVLNKPWRPLTFSPTWLTVSEGANATFTCSFSNWSEDLKLNWYRLSPSNQTEKQAAFCNGYSQPVRDARFQIVQLPNGHDFHMNILDARRNDSGIYLCGAISLPPKAQIKESPGAELVVTERILETPTRYPRPSPKPEGQFQGLVIVIMSVLVGIPVLLLLAWALAAFCSTGMSEAREAGRKEDPPKEAHAAAPVPSVAYEELDFQGREKTPEPAPCVHTEYATIVFTEGLDASAIGRRGSADGPQGPRPPRHEDGHCSWPL
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: Pdcd1 programmed cell death 1 [ Rattus norvegicus ]
• Official Symbol: PDCD1
• Synonyms: PDCD1; programmed cell death 1; programmed cell death protein 1
• Gene ID: 301626
• mRNA Refseq: NM_001106927
• Protein Refseq: NP_001100397
• UniProt ID: D3ZIN8