Recombinant Rat Interleukin 7

• Cat.No.: Il7-174R
• Product Overview: Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues. It was expressed inE.Coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: Non
• Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive.
• Specific Activity: > 5 x 106 units/mg.
• Purity: > 98% by SDS-PAGE and HPLC analysis.
• Endotoxin Level: < 0.1 ng/μg of IL-7.
• Stabilizer: None.
• Formulation: Lyophilized.
• Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
• Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-7 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Il7 interleukin 7 [ Rattus norvegicus ]
• Synonyms: interleukin 7; Il7
• Gene ID: 25647
• mRNA Refseq: NM_013110
• Protein Refseq: NP_037242
• UniProt ID: P56478
• Chromosome Location: 2q23
• Pathway: Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway
• Function: interleukin-7 receptor binding; cytokine activity; growth factor activity; protein binding