Recombinant Rat Gsdmd Protein, His-tagged

• Cat.No.: Gsdmd-1601R
• Product Overview: Recombinant Rat Gsdmd Protein (Met1-Pro326) with N-His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: Met1-Pro326
• Description: Predicted to enable phospholipid binding activity and wide pore channel activity. Predicted to be involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Predicted to act upstream of or within cellular response to extracellular stimulus. Predicted to be located in several cellular components, including cytosol; extracellular space; and nucleoplasm. Predicted to be part of NLRP3 inflammasome complex. Orthologous to human GSDMD (gasdermin D).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 39.5 kDa
  Accurate Molecular Mass: 40 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Gsdmd gasdermin D [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Gsdmd
• Synonyms: GSDMD; gasdermin D; gasdermin-D; gasdermin domain containing 1; Gsdmdc1
• Gene ID: 315084
• mRNA Refseq: NM_001130553
• Protein Refseq: NP_001124025
• UniProt ID: A0A096MJ11