Recombinant Rat Fgf23 protein, His-tagged

• Cat.No.: Fgf23-493R
• Product Overview: Recombinant Rat Fgf23(aa 25-251) fused with His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: 25-251 a.a.
• Description: FGF23 is a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR).
• Form: 20 mM Tris, pH 8.0, 500 mM NaCl, 50% glycerol
• Molecular Mass: 29.6 Kd
• AA Sequence: YSDTSPLLGS NWGSLTHLYT ATARNSYHLQ IHRDGHVDGTPHQTIYSALM ITSEDAGSVV IIGAMTRRFL CMDLRGNIFGSYHFSPENCR FRQWTLENGY DVYLSPKHHY LVSLGRSKRIFQPGTNPPPF SQFLARRNEV PLLHFYTARP RRHTRSAEDPPERDPLNVLK PRPRATPIPV SCSRELPSAE EGGPAASDPLGVLRRGRGDA RRGAGGTDRC RPFPRFV
• Storage: Long term: -80 centigrade; Short term: -20 centigrade. Avoid freeze-thaw cycles.

Gene Information

• Gene Name: Fgf23 fibroblast growth factor 23 [ Rattus norvegicus ]
• Official Symbol: Fgf23
• Synonyms: FGF23; fibroblast growth factor 23; FGF-23
• Gene ID: 170583
• mRNA Refseq: NM_130754
• Protein Refseq: NP_570110
• UniProt ID: Q8VI82
• Chromosome Location: 4q42
• Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1c and Klotho ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem
• Function: fibroblast growth factor receptor binding; fibroblast growth factor receptor binding; growth factor activity; type 1 fibroblast growth factor receptor binding; type 1 fibroblast growth factor receptor binding