Recombinant Rat F7 Protein, His&GST-tagged

• Cat.No.: F7-911R
• Product Overview: Recombinant Rat F7 Protein (Ile194-Leu446) with His&GST tag was expressed in E. coli.

Specification

• Description: Enables endopeptidase activity and signaling receptor binding activity. Involved in several processes, including response to anticoagulant; response to peptide hormone; and response to thyroxine. Located in extracellular space and vesicle. Used to study asthma; diabetes mellitus; and type 2 diabetes mellitus. Biomarker of several diseases, including bilirubin metabolic disorder; familial hyperlipidemia; hypertension; hypothyroidism; and prothrombin deficiency. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebral infarction; diabetes mellitus (multiple); factor VII deficiency; and obesity. Orthologous to human F7 (coagulation factor VII).
• Source: E. coli
• Species: Rat
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 58.0 kDa; Accurate Molecular Mass: 61 kDa
• Protein length: Ile194-Leu446
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: F7 coagulation factor VII (serum prothrombin conversion accelerator) [ Rattus norvegicus (Norway rat) ]
• Official Symbol: F7
• Synonyms: F7; coagulation factor VII (serum prothrombin conversion accelerator); coagulation factor VII; serum prothrombin conversion accelerator
• Gene ID: 260320
• mRNA Refseq: NM_152846
• Protein Refseq: NP_690059
• UniProt ID: Q8K3U6