Recombinant Mouse F7 Protein, MYC/DDK-tagged

• Cat.No.: F7-1000M
• Product Overview: Purified recombinant protein of full-length mouse coagulation factor VII (F7), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: This gene encodes a vitamin K-dependent serine protease that plays a critical role in the extrinsic pathway of blood coagulation. Upon contact with tissue factor III (TF III), the encoded protein forms an activated complex termed TF-FVIIa that initiates the coagulation cascade involving other coagulation factors, ultimately resulting in a fibrin clot. Complete lack of the encoded protein in mice results in in perinatal lethality due to bleeding from normal blood vessels.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 50.3 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: F7 coagulation factor VII [ Mus musculus (house mouse) ]
• Official Symbol: F7
• Synonyms: F7; coagulation factor VII; Cf7; FVII; AI132620; coagulation factor VII; serum prothrombin conversion accelerator; EC 3.4.21.21
• Gene ID: 14068
• mRNA Refseq: NM_010172
• Protein Refseq: NP_034302
• UniProt ID: P70375