Recombinant Rat DHODH Protein

• Cat.No.: DHODH-1859R
• Product Overview: Recombinant Rat DHODH Protein was expressed in Insect cell.

Specification

• Species: Rat
• Source: Insect Cells
• Protein Length: 31-395 aa
• Description: Enables FMN binding activity; dihydroorotate dehydrogenase activity; and ubiquinone binding activity. Involved in several processes, including 'de novo' pyrimidine nucleobase biosynthetic process; lactation; and response to L-arginine. Located in mitochondrial inner membrane and neuronal cell body. Human ortholog(s) of this gene implicated in postaxial acrofacial dysostosis. Orthologous to human DHODH (dihydroorotate dehydrogenase (quinone)).
• Form: 0.2 μm sterile filtered 10 mM Tris-HCl, 1 mM EDTA, pH 8.0, 20% glycerol.
• Molecular Mass: 41.9 kDa
• AA Sequence: TGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR
• Endotoxin: <1.0 EU per 1μg of the protein by the LAL method.
• Purity: ≥85%, by SDS-PAGE
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: Dhodh dihydroorotate dehydrogenase (quinone) [ Rattus norvegicus (Norway rat) ]
• Official Symbol: DHODH
• Synonyms: URA1; POADS; DHOdehase
• Gene ID: 65156
• mRNA Refseq: NM_001008553.2
• Protein Refseq: NP_001008553.1
• UniProt ID: Q63707