Recombinant Rat Col1a2 Protein, His-tagged

• Cat.No.: Col1a2-818R
• Product Overview: Recombinant Rat Col1a2 Protein (Val1109-Lys1372) with His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: Val1109-Lys1372
• Description: Predicted to enable several functions, including identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Predicted to be an extracellular matrix structural constituent. Involved in cellular response to retinoic acid; cellular response to thyroid hormone stimulus; and response to norepinephrine. Predicted to be located in endoplasmic reticulum. Predicted to be part of collagen type I trimer. Predicted to be active in extracellular matrix and extracellular space. Biomarker of hypothyroidism; muscular atrophy; pulmonary fibrosis; and ureteral obstruction. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome (multiple); heart valve disease; intracranial aneurysm; osteogenesis imperfecta (multiple); and osteoporosis. Orthologous to human COL1A2 (collagen type I alpha 2 chain).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.2 kDa; Accurate Molecular Mass: 33 kDa
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Col1a2 collagen, type I, alpha 2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Col1a2
• Synonyms: COL1A2; collagen, type I, alpha 2; collagen alpha-2(I) chain; alpha-2 type I collagen; procollagen, type I, alpha 2
• Gene ID: 84352
• mRNA Refseq: NM_053356
• Protein Refseq: NP_445808
• UniProt ID: P02466