Recombinant Rat Coagulation Factor XII

• Cat.No.: F12 -101R
• Product Overview: Recombinant insect cell derived rat Factor XII is a single chain glycoprotein purified by ion exchange chromatography. Factor XII is converted, principally from the action of kallikrein, into an active serine protease (Factor α-XIIa) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. Custom mutants of Factor XII are also available, please contact us for more details.

Specification

• Source: Insect cell
• Species: Rat
• Form: Frozen liquid
• Molecular Mass: 75,000 (Approximate)
• Purity: >95% by SDS-PAGE analysis
• Usage: For in vitro laboratory use only
• Notes: Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
• Storage: -70°C
• Concentration: 0.25 mg/ml
• Storage Buffer: 4 mM Sodium Acetate; 0.15 M NaCl; pH 5.3
• Shipping: Dry ice
• Tag: Non

Gene Information

• Gene Name: F12 coagulation factor XII (Hageman factor) [ Rattus norvegicus ]
• Official Symbol: F12
• Synonyms: F12; coagulation factor XII (Hageman factor); coagulation factor XII; factor XII; hageman factor; HAF
• Gene ID: 306761
• mRNA Refseq: NM_001014006
• Protein Refseq: NP_001014028
• UniProt ID: D3ZTE0
• Chromosome Location: 17p14
• Pathway: Blood Clotting Cascade, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem; Intrinsic Pathway, organism-specific biosystem
• Function: binding; peptidase activity; peptidase activity; serine-type aminopeptidase activity; serine-type endopeptidase activity; serine-type endopeptidase activity