Recombinant Rat Casp4 Protein, His-tagged

• Cat.No.: Casp4-626R
• Product Overview: Recombinant Rat Casp4 Protein (Met1-Asn373) with His tag was expressed in E. coli.

Specification

• Description: Enables scaffold protein binding activity. Predicted to be involved in several processes, including cellular response to amyloid-beta; positive regulation of tumor necrosis factor-mediated signaling pathway; and protein autoprocessing. Predicted to act upstream of or within ectopic germ cell programmed cell death; positive regulation of interleukin-1 beta production; and pyroptosis. Located in neuron projection and neuronal cell body. Part of protein-containing complex. Orthologous to human CASP4 (caspase 4).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 46.4 kDa; Accurate Molecular Mass: 46 kDa
• Protein length: Met1-Asn373
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Casp4 caspase 4, apoptosis-related cysteine peptidase [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Casp4
• Synonyms: CASP4; caspase 4, apoptosis-related cysteine peptidase; caspase 4; caspase 11; Casp11; MGC124949
• Gene ID: 114555
• mRNA Refseq: NM_053736
• Protein Refseq: NP_446188
• UniProt ID: E9PSM0