Recombinant Porcine transmissible gastroenteritis coronavirus pp1a Protein (G2998-A3296), His-tagged

• Cat.No.: pp1a-1563P
• Product Overview: Recombinant Porcine transmissible gastroenteritis coronavirus 6His-TEV-(G)-S-PEDV-NSP5(G2998-A3296) (C3141A) protein with a His tag was expressed in E. coli

Specification

• Species: Porcine transmissible gastroenteritis coronavirus
• Source: E.coli
• Tag: His
• ProteinLength: G2998-A3296
• Description: The papain-like proteinase 1 (PLP1) and papain-like proteinase 2 (PLP2) are responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PLP2 possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48' and 'Lys-63' linked polyubiquitin chains from cellular substrates. PLP2 also antagonizes innate immune induction of type I interferon by blocking the nuclear translocation of host IRF-3.
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Official Symbol: pp1a
• Synonyms: Replicase polyprotein 1a; Replicase polyprotein 1a; pp1a; ORF1a polyprotein
• UniProt ID: P0C6V2